Dimethylformamide → 3-[6-(4-ethylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]-N-isoxazol-3-yl-4-methylbenzamide
Reaction equation
[CH2:49]([Cl:50])[Cl:51].[CH3:1][c:2]1[c:3](-[n:11]2[cH:12][n:13][c:14]3[cH:15][cH:16][c:17]([N:22]4[CH2:23][CH2:24][N:25]([CH2:28][CH3:29])[CH2:26][CH2:27]4)[cH:18][c:19]3[c:20]2=[O:21])[cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1.[CH3:52][CH2:53][O:54][C:55](=[O:56])[CH3:57].[CH:40]([N:41]([CH2:42][CH3:43])[CH:44]([CH3:45])[CH3:46])([CH3:47])[CH3:48].[NH2:34][c:35]1[n:36][o:37][cH:38][cH:39]1.[O:58]=[CH:59][N:60]([CH3:61])[CH3:62].[S:30]([Cl:31])([Cl:32])=[O:33]>>[CH3:1][c:2]1[c:3](-[n:11]2[cH:12][n:13][c:14]3[cH:15][cH:16][c:17]([N:22]4[CH2:23][CH2:24][N:25]([CH2:28][CH3:29])[CH2:26][CH2:27]4)[cH:18][c:19]3[c:20]2=[O:21])[cH:4][c:5]([C:6](=[O:8])[NH:34][c:35]2[n:36][o:37][cH:38][cH:39]2)[cH:9][cH:10]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-40e2e1cbbdc744de8668c7587fbb32be
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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