Dimethylformamide → 4-chloro-N-(3-methoxy-5-methylpyrazin-2-yl)-N-[2-(trimethylsilyl)ethoxymethyl]pyridine-3-sulphonamide
Reaction equation
[CH3:1][Si:2]([CH2:3][CH2:4][O:5][CH2:6][Cl:7])([CH3:8])[CH3:9].[CH3:39][CH2:40][O:41][C:42](=[O:43])[CH3:44].[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cl:10][c:11]1[c:12]([S:17](=[O:18])(=[O:19])[NH:20][c:21]2[n:22][cH:23][c:24]([CH3:29])[n:25][c:26]2[O:27][CH3:28])[cH:13][n:14][cH:15][cH:16]1.[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[CH3:1][Si:2]([CH2:3][CH2:4][O:5][CH2:6][N:20]([S:17]([c:12]1[c:11]([Cl:10])[cH:16][cH:15][n:14][cH:13]1)(=[O:18])=[O:19])[c:21]1[n:22][cH:23][c:24]([CH3:29])[n:25][c:26]1[O:27][CH3:28])([CH3:8])[CH3:9]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-940857be2dc649da8ce56d403cb3f4ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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