Tetrahydrofuran → 5-[(2-Fluoro-4-iodophenyl)amino]-2-phenylisonicotinic acid
Reaction equation
[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46].[F:11][c:12]1[cH:13][n:14][c:15](-[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[cH:16][c:17]1[C:18](=[O:19])[OH:20].[F:27][c:28]1[c:29]([NH2:30])[cH:31][cH:32][c:33]([I:35])[cH:34]1.[Li+:10]>>[c:12]1([NH:30][c:29]2[c:28]([F:27])[cH:34][c:33]([I:35])[cH:32][cH:31]2)[cH:13][n:14][c:15](-[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[cH:16][c:17]1[C:18](=[O:19])[OH:20]Participants
7
Sources & evidence
- ORD record
- ord-940aae3d59b4465b9f7c925118be3441
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…