Tetrahydrofuran → 1-(1-Trifluoromethyl-cyclopropanecarbonyl)-piperidine-4-carboxylic acid ethyl ester
Reaction equation
[C:1]([n:2]1[cH:3][cH:4][n:5][cH:6]1)([n:7]1[cH:8][cH:9][n:10][cH:11]1)=[O:12].[CH2:23]([CH3:24])[O:25][C:26](=[O:27])[CH:28]1[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]1.[F:13][C:14]([C:15]1([C:18](=[O:19])[OH:20])[CH2:16][CH2:17]1)([F:21])[F:22].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[F:13][C:14]([C:15]1([C:18](=[O:19])[N:31]2[CH2:30][CH2:29][CH:28]([C:26]([O:25][CH2:23][CH3:24])=[O:27])[CH2:33][CH2:32]2)[CH2:16][CH2:17]1)([F:21])[F:22]Participants
5
Sources & evidence
- ORD record
- ord-028ff1f3bb1841d694c06a15f9ede5d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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