Dimethylformamide → HCID 66621106, compound

HRID 1546850Notes

Reaction equation

HRID 1546850 reaction equation
[CH3:1][O:2][C:3]([NH:4][CH:5]([CH:6]([CH3:7])[CH3:8])[C:9](=[O:10])[N:11]1[CH:12]([c:16]2[nH:17][c:18]([C:21]3=[CH:22][CH:23]4[CH:24]([S:25]3)[CH:26]=[C:27]([Br:29])[S:28]4)[cH:19][n:20]2)[CH2:13][CH2:14][CH2:15]1)=[O:30].[CH3:31][O:32][C:33]([NH:34][CH:35]([CH:36]([CH3:37])[CH3:38])[C:39](=[O:40])[N:41]1[CH:42]([c:46]2[nH:47][c:48]([C:51]#[CH:52])[cH:49][n:50]2)[CH2:43][CH2:44][CH2:45]1)=[O:53].[CH3:54][CH2:55][N:56]([CH2:57][CH3:58])[CH2:59][CH3:60].[Cu:143][I:144].[O:61]=[CH:62][N:63]([CH3:64])[CH3:65].[cH:66]1[cH:67][cH:68][c:69]([P:70]([Pd:71]([P:72]([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)([P:91]([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[P:110]([c:111]2[cH:112][cH:113][cH:114][cH:115][cH:116]2)([c:117]2[cH:118][cH:119][cH:120][cH:121][cH:122]2)[c:123]2[cH:124][cH:125][cH:126][cH:127][cH:128]2)([c:129]2[cH:130][cH:131][cH:132][cH:133][cH:134]2)[c:135]2[cH:136][cH:137][cH:138][cH:139][cH:140]2)[cH:141][cH:142]1>>[CH3:1][O:2][C:3]([NH:4][CH:5]([CH:6]([CH3:7])[CH3:8])[C:9](=[O:10])[N:11]1[CH:12]([c:16]2[nH:17][c:18]([C:21]3=[CH:22][CH:23]4[CH:24]([S:25]3)[CH:26]=[C:27]([C:52]#[C:51][c:48]3[nH:47][c:46]([CH:42]5[N:41]([C:39]([CH:35]([NH:34][C:33]([O:32][CH3:31])=[O:53])[CH:36]([CH3:37])[CH3:38])=[O:40])[CH2:45][CH2:44][CH2:43]5)[n:50][cH:49]3)[S:28]4)[cH:19][n:20]2)[CH2:13][CH2:14][CH2:15]1)=[O:30]

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66621112(1-{2-[5-(5-Bromo-3a,6a-dihydro-thieno[3,2-b]thiophen-2-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl esterHCID 76818854{1-[2-(5-Ethynyl-1H-imidazol-2-yl)-pyrrolidine-1-carbonyl]-2-methyl-propyl}-carbamic acid methyl esterHCID 178420554HCID 178420554, compound

Product 1

HCID 66621106HCID 66621106, compound

Sources & evidence

ORD record
ord-c537ccdb47ab4f31b4acee39707675dd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…