Tetrahydrofuran → 2-(4-Fluorophenyl)-5-[(tetra-hydro-2-pyranyloxy)methyl]pyridine
Reaction equation
[Br:2][c:3]1[cH:4][cH:5][c:6]([F:9])[cH:7][cH:8]1.[Cl:10][c:11]1[n:12][cH:13][c:14]([CH2:17][O:18][CH:19]2[O:20][CH2:21][CH2:22][CH2:23][CH2:24]2)[cH:15][cH:16]1.[Mg:1].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[c:3]1(-[c:11]2[n:12][cH:13][c:14]([CH2:17][O:18][CH:19]3[O:20][CH2:21][CH2:22][CH2:23][CH2:24]3)[cH:15][cH:16]2)[cH:4][cH:5][c:6]([F:9])[cH:7][cH:8]1Participants
5
Sources & evidence
- ORD record
- ord-ce5ed4be0ac8438ab6784a67cd4a601d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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