Hydrochloric Acid → Benzyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

HRID 1547594Notes

Reaction equation

HRID 1547594 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[CH:11]1[N:12]([C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[CH2:13][c:14]2[cH:15][c:16]([O:23][CH3:24])[c:17]([O:21][CH3:22])[cH:18][c:19]2[CH2:20]1.[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[CH:33]([OH:34])([CH3:35])[CH3:36].[ClH:32]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[CH:11]1[NH:12][CH2:13][c:14]2[cH:15][c:16]([O:23][CH3:24])[c:17]([O:21][CH3:22])[cH:18][c:19]2[CH2:20]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 1140TolueneHCID 3776IsopropanolHCID 8857Ethyl AcetateHCID 700268633-O-benzyl 2-O-tert-butyl 6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2,3-dicarboxylate

Product 1

HCID 13044264Benzyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

Sources & evidence

ORD record
ord-ba1ef5419c714fe7a1f840d1868d63af
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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