Dichloromethane → 4-fluoro-benzenesulfonic acid 2-amino-3-cyclopropanecarbonyl-3H-benzoimidazol-5-yl ester

HRID 1547736Notes

Reaction equation

HRID 1547736 reaction equation
[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[CH:29]1([C:32](=[O:33])[Cl:34])[CH2:30][CH2:31]1.[Cl:42][CH2:43][Cl:44].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[NH2:8][c:9]1[n:10][c:11]2[c:12]([nH:13]1)[cH:14][cH:15][c:16]([O:18][S:19](=[O:20])(=[O:21])[c:22]1[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]1)[cH:17]2>>[NH2:8][c:9]1[n:10]([C:32]([CH:29]2[CH2:30][CH2:31]2)=[O:33])[c:11]2[c:12]([n:13]1)[cH:14][cH:15][c:16]([O:18][S:19](=[O:20])(=[O:21])[c:22]1[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]1)[cH:17]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 8471TriethylamineHCID 77637Cyclopropanecarbonyl chlorideHCID 178508204HCID 178508204, compound

Product 1

HCID 865960754-fluoro-benzenesulfonic acid 2-amino-3-cyclopropanecarbonyl-3H-benzoimidazol-5-yl ester

Sources & evidence

ORD record
ord-a66c8252fa8a41d5a1b4948ae83cb389
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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