Hydrochloric Acid → 2-{6-(4-Chloro-benzyl)-2-[1-(6-methyl-pyrimidin-4-yl)-piperidin-4-ylamino]-pyrimidin-4-yl}-propan-2-ol
Reaction equation
[CH3:3][c:4]1[cH:5][c:6]([N:10]2[CH2:11][CH2:12][CH:13]([NH2:16])[CH2:14][CH2:15]2)[n:7][cH:8][n:9]1.[CH3:45][N:46]1[CH2:47][CH2:48][CH2:49][C:50]1=[O:51].[CH:17]([N:18]([CH2:19][CH3:20])[CH:21]([CH3:22])[CH3:23])([CH3:24])[CH3:25].[Cl:26][c:27]1[n:28][c:29]([CH2:37][c:38]2[cH:39][cH:40][c:41]([Cl:44])[cH:42][cH:43]2)[cH:30][c:31]([C:33]([CH3:34])([CH3:35])[OH:36])[n:32]1.[ClH:1].[ClH:2].[O:52]1[CH2:53][CH2:54][O:55][CH2:56][CH2:57]1.[OH2:58]>>[CH3:3][c:4]1[cH:5][c:6]([N:10]2[CH2:11][CH2:12][CH:13]([NH:16][c:27]3[n:28][c:29]([CH2:37][c:38]4[cH:39][cH:40][c:41]([Cl:44])[cH:42][cH:43]4)[cH:30][c:31]([C:33]([CH3:34])([CH3:35])[OH:36])[n:32]3)[CH2:14][CH2:15]2)[n:7][cH:8][n:9]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-925ee37b18a84fbbb69cfe1624dae215
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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