2,6-Lutidine → Hydrochloric Acid

HRID 1550084Notes

Reaction equation

HRID 1550084 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[cH:9][c:10]([CH:18]2[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]2)[c:11]2[cH:12][c:13]([OH:17])[cH:14][cH:15][c:16]12.[F:25][c:26]1[c:27]([S:33](=[O:34])(=[O:35])[Cl:36])[c:28]([F:32])[cH:29][cH:30][cH:31]1.[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1.[n:37]1[c:38]([CH3:39])[cH:40][cH:41][cH:42][c:43]1[CH3:44]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[cH:9][c:10]([CH:18]2[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]2)[c:11]2[cH:12][c:13]([O:17][S:33]([c:27]3[c:26]([F:25])[cH:31][cH:30][cH:29][c:28]3[F:32])(=[O:34])=[O:35])[cH:14][cH:15][c:16]12.[ClH:36]

Participants

6

Reactant 4

HCID 79372,6-LutidineHCID 8028TetrahydrofuranHCID 27342712,6-Difluorobenzenesulfonyl chlorideHCID 179801081-Benzyl-3-(1-methylpiperidin-4-yl)-5-hydroxy-1H-indole

Product 2

HCID 313Hydrochloric AcidHCID 10300394[1-Benzyl-3-(1-methylpiperidin-4-yl)indol-5-yl] 2,6-difluorobenzenesulfonate

Sources & evidence

ORD record
ord-61b457532e094d28ab97e768b5b7ab32
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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