Chloride → (2-Chloropyridin-3-yl)(cyclopropyl)methanone

HRID 1550818Notes

Reaction equation

HRID 1550818 reaction equation
[CH2:17]([Li:18])[CH2:19][CH2:20][CH3:21].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH:1]1([Sn:4]([CH2:5][CH2:6][CH2:7][CH3:8])([CH2:9][CH2:10][CH2:11][CH3:12])[CH2:13][CH2:14][CH2:15][CH3:16])[CH2:2][CH2:3]1.[Cl-:22].[Cl:23][c:24]1[c:25]([C:26](=[O:27])[OH:28])[cH:29][cH:30][cH:31][n:32]1.[Cu:38][I:39]>>[CH:1]1([C:26]([c:25]2[c:24]([Cl:23])[n:32][cH:31][cH:30][cH:29]2)=[O:28])[CH2:2][CH2:3]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 762582-Chloronicotinic acidHCID 10947505CyclopropyltributylstannaneHCID 178418339Butyllithium

Product 1

HCID 10749922(2-Chloropyridin-3-yl)(cyclopropyl)methanone

Sources & evidence

ORD record
ord-7166bf8b8b6b438b888ea8c808af4a09
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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