Potassium Cation → 2-Chloro-4-phenylpyrimidine

HRID 1550893Notes

Reaction equation

HRID 1550893 reaction equation
[C:33]([O:34][CH3:35])([CH3:36])([CH3:37])[CH3:38].[CH3:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[CH3:31][OH:32].[Cl:7][c:8]1[n:9][cH:10][cH:11][c:12]([Cl:14])[n:13]1.[K+:1].[K+:2].[O-:3][C:4]([O-:5])=[O:6].[OH2:39].[c:15]1([B:21]([OH:22])[OH:23])[cH:16][cH:17][cH:18][cH:19][cH:20]1>>[Cl:7][c:8]1[n:9][cH:10][cH:11][c:12](-[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[n:13]1

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 887MethanolHCID 962WaterHCID 1140TolueneHCID 15413tert-Butyl methyl etherHCID 19660Carbonate IonHCID 66827Phenylboronic AcidHCID 775312,4-Dichloropyrimidine

Product 1

HCID 6053562-Chloro-4-phenylpyrimidine

Sources & evidence

ORD record
ord-9b18952e6b0241208f61d8e2678b0686
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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