Potassium Cation → 6-Fluoro-3-((2-methoxyethoxy)methoxy)-2-(trifluoromethyl)pyridine

HRID 1551234Notes

Reaction equation

HRID 1551234 reaction equation
[CH3:31][N:32]1[CH2:33][CH2:34][CH2:35][C:36]1=[O:37].[CH3:8][Si:9]([C:10]([F:11])([F:12])[F:13])([CH3:14])[CH3:15].[Cu:38][I:39].[F-:1].[F:16][c:17]1[cH:18][cH:19][c:20]([O:24][CH2:25][O:26][CH2:27][CH2:28][O:29][CH3:30])[c:21]([I:23])[n:22]1.[K+:2].[O:3]=[CH:4][N:5]([CH3:6])[CH3:7]>>[C:10]([F:11])([F:12])([F:13])[c:21]1[c:20]([O:24][CH2:25][O:26][CH2:27][CH2:28][O:29][CH3:30])[cH:19][cH:18][c:17]([F:16])[n:22]1

Participants

8

Reactant 7

HCID 813Potassium CationHCID 6228DimethylformamideHCID 13387N-methyl-2-pyrrolidoneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 28179Fluoride IonHCID 552549(Trifluoromethyl)trimethylsilaneHCID 86628005HCID 86628005, compound

Product 1

HCID 670975666-Fluoro-3-((2-methoxyethoxy)methoxy)-2-(trifluoromethyl)pyridine

Sources & evidence

ORD record
ord-ac66cff074414f50996ec5254abf5e7a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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