Picolinic acid → Diethyl 2-(5-bromopyridin-2-yl)malonate
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([I:8])[n:6][cH:7]1.[C:20](=[O:21])([O-:22])[O-:23].[CH2:35]1[O:36][CH2:37][CH2:38][O:39][CH2:40]1.[CH2:9]([CH3:10])[O:11][C:12]([CH2:13][C:14](=[O:15])[O:16][CH2:17][CH3:18])=[O:19].[Cs+:24].[Cs+:25].[Cu:41][I:42].[OH:26][C:27]([c:28]1[n:29][cH:30][cH:31][cH:32][cH:33]1)=[O:34]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:13]([C:12]([O:11][CH2:9][CH3:10])=[O:19])[C:14](=[O:15])[O:16][CH2:17][CH3:18])[n:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-0dc2fac0244f45c3b5fd1f8067193581
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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