Hydrochloric Acid → tert-Butyl 4-oxopiperidine-1-carboxylate

HRID 155124Notes

Reaction equation

HRID 155124 reaction equation
[C:10](=[O:11])([OH:12])[O-:13].[C:15](=[O:16])([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[O:22][C:23]([O-:24])=[O:25].[CH3:26][CH2:27][O:28][C:29](=[O:30])[CH3:31].[ClH:1].[NH:3]1[CH2:4][CH2:5][C:6](=[O:9])[CH2:7][CH2:8]1.[Na+:14].[OH2:2]>>[N:3]1([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:4][CH2:5][C:6](=[O:9])[CH2:7][CH2:8]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 923Sodium ionHCID 962WaterHCID 8857Ethyl AcetateHCID 337214-PiperidoneHCID 22064466Tert-butyldicarbonate

Product 1

HCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Sources & evidence

ORD record
ord-1b7ce4eeb91046e6a19e5250aa9344bd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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