Hydrochloric Acid → 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-(2-methoxy-2,3-dihydro-1H-inden-1-yl)-3,4-dihydro-1H-isoquinoline-2-carboxamide
Reaction equation
[CH3:12][O:13][CH:14]1[CH:15]([NH2:23])[c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]2[CH2:22]1.[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:32][N:33]1[CH2:34][CH2:35][N:36]([c:39]2[n:40][c:41]([NH2:55])[n:42][c:43](-[c:45]3[cH:46][cH:47][c:48]4[c:53]([cH:54]3)[CH2:52][NH:51][CH2:50][CH2:49]4)[cH:44]2)[CH2:37][CH2:38]1.[CH3:5][c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1.[CH3:62][C:63]#[N:64].[Cl:1][C:2]([Cl:3])=[O:4].[ClH:24].[ClH:56].[O:57]1[CH2:58][CH2:59][CH2:60][CH2:61]1>>[C:2](=[O:4])([NH:23][CH:15]1[CH:14]([O:13][CH3:12])[CH2:22][c:21]2[c:16]1[cH:17][cH:18][cH:19][cH:20]2)[N:51]1[CH2:50][CH2:49][c:48]2[cH:47][cH:46][c:45](-[c:43]3[n:42][c:41]([NH2:55])[n:40][c:39]([N:36]4[CH2:35][CH2:34][N:33]([CH3:32])[CH2:38][CH2:37]4)[cH:44]3)[cH:54][c:53]2[CH2:52]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-c63dccaa85614cb9afffbdbf62497924
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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