1,2-Dichloroethane → 4-(6-Chloro-2,3-dihydro-indol-1-yl)-6-methyl-pyrido[3,4-d]pyrimidine

HRID 1552223Notes

Reaction equation

HRID 1552223 reaction equation
[C:32]([Cl:33])([Cl:34])([Cl:35])[Cl:36].[CH3:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7][nH:8][c:9]2=[O:10])[cH:11][n:12]1.[Cl:39][c:40]1[cH:41][cH:42][c:43]2[c:47]([cH:48]1)[NH:46][CH2:45][CH2:44]2.[Cl:49][CH2:50][CH2:51][Cl:52].[N:37]#[N:38].[c:13]1([P:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[cH:27][cH:28][cH:29][cH:30][cH:31]1>>[CH3:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7][n:8][c:9]2[N:46]2[CH2:45][CH2:44][c:43]3[cH:42][cH:41][c:40]([Cl:39])[cH:48][c:47]32)[cH:11][n:12]1

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 947NitrogenHCID 5943Carbon TetrachlorideHCID 11776TriphenylphosphineHCID 2585676-Chloro-2,3-dihydro-1h-indoleHCID 1359920016Methyl-pyrido[3,4-d]pyrimid-4one

Product 1

HCID 184732884-(6-Chloro-2,3-dihydro-indol-1-yl)-6-methyl-pyrido[3,4-d]pyrimidine

Sources & evidence

ORD record
ord-31951be97cbb4ae6b90f2cbc0a0903cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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