Phthalimide → tert-Butyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]piperidine-1-carboxylate
Reaction equation
[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[O:1]=[C:2]([O:3][CH:4]([CH3:5])[CH3:6])[N:7]=[N:8][C:9]([O:10][CH:11]([CH3:12])[CH3:13])=[O:14].[O:30]=[C:31]1[NH:32][C:33](=[O:34])[c:35]2[cH:36][cH:37][cH:38][cH:39][c:40]21.[OH:15][CH2:16][CH:17]1[CH2:18][N:19]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:20][CH2:21][CH2:22]1.[c:41]1([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[cH:55][cH:56][cH:57][cH:58][cH:59]1>>[CH2:16]([CH:17]1[CH2:18][N:19]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:20][CH2:21][CH2:22]1)[N:32]1[C:31](=[O:30])[c:40]2[c:35]([cH:36][cH:37][cH:38][cH:39]2)[C:33]1=[O:34]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-602a12d4f0864f5db7f19c3423150762
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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