Imidazole → 5-chloro-N-cyclopentyl-2-[4-(2-pyrazol-1-ylethyl)-4,5-dihydro-1,3-thiazol-2-yl]-1H-indol-7-amine
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([C:17]3=[N:21][CH:20]([CH2:22][CH2:23][OH:24])[CH2:19][S:18]3)[nH:7][c:8]2[c:9]([NH:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:10]1.[H-:36].[I:25].[Na+:37].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[nH:26]1[cH:27][cH:28][n:29][cH:30]1.[nH:31]1[n:32][cH:33][cH:34][cH:35]1>>[Cl:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([C:17]3=[N:21][CH:20]([CH2:22][CH2:23][n:31]4[n:32][cH:33][cH:34][cH:35]4)[CH2:19][S:18]3)[nH:7][c:8]2[c:9]([NH:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:10]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d92456ca8b0743cb8e38da4e1395118f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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