Acetonitrile → 5-(2-Butoxy-5-trimethylsilylethynyl-3-pyridinyl)-2-[2-(dimethylamino)-ethyl]-3-ethyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Reaction equation
[CH2:8]([CH2:9][CH2:10][CH3:11])[O:12][c:13]1[n:14][cH:15][c:16]([I:36])[cH:17][c:18]1-[c:19]1[nH:20][c:21](=[O:35])[c:22]2[c:23]([n:24]1)[c:25]([CH2:33][CH3:34])[n:26]([CH2:28][CH2:29][N:30]([CH3:31])[CH3:32])[n:27]2.[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[CH:6].[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[CH3:44][C:45]#[N:46].[I-:7].[Pd:47]([Cl:48])[Cl:49].[c:50]1([P:51]([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[cH:64][cH:65][cH:66][cH:67][cH:68]1.[c:69]1([P:70]([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[cH:83][cH:84][cH:85][cH:86][cH:87]1>>[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[C:6][c:16]1[cH:15][n:14][c:13]([O:12][CH2:8][CH2:9][CH2:10][CH3:11])[c:18](-[c:19]2[nH:20][c:21](=[O:35])[c:22]3[c:23]([n:24]2)[c:25]([CH2:33][CH3:34])[n:26]([CH2:28][CH2:29][N:30]([CH3:31])[CH3:32])[n:27]3)[cH:17]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b3353708146c4ac28615b349e2143233
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…