Phthalimide → 2-(1-(5,7-Difluoroquinolin-6-yl)ethyl)isoindoline-1,3-dione
Reaction equation
[C:49]1(=[O:59])[NH:50][C:51](=[O:58])[c:52]2[cH:53][cH:54][cH:55][cH:56][c:57]21.[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[F:34][c:35]1[c:36]2[cH:37][cH:38][cH:39][n:40][c:41]2[cH:42][c:43]([F:48])[c:44]1[CH:45]([CH3:46])[OH:47].[N:1]([C:2]([O:3][CH:4]([CH3:5])[CH3:6])=[O:7])=[N:8][C:9]([O:10][CH:11]([CH3:12])[CH3:13])=[O:14].[c:15]1([P:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[F:34][c:35]1[c:36]2[cH:37][cH:38][cH:39][n:40][c:41]2[cH:42][c:43]([F:48])[c:44]1[CH:45]([CH3:46])[N:50]1[C:49](=[O:59])[c:57]2[c:52]([cH:53][cH:54][cH:55][cH:56]2)[C:51]1=[O:58]Participants
6
Sources & evidence
- ORD record
- ord-8190be33ff4d4b47bc3d9db9618fedb6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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