Citric Acid → 1-(2-Bromo-4-fluorophenyl)-2-phenylethanone

HRID 1554253Notes

Reaction equation

HRID 1554253 reaction equation
[Br:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][cH:7][c:8]([F:10])[cH:9]1.[CH2:12]([c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1)[Mg+:19].[Cl-:11].[Cl:21][CH2:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[Mg:20].[OH:29][C:30]([CH2:31][C:32]([C:33](=[O:34])[OH:35])([CH2:36][C:37](=[O:38])[OH:39])[OH:40])=[O:41]>>[Br:1][c:2]1[c:3]([C:4]([CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)=[O:29])[cH:6][cH:7][c:8]([F:10])[cH:9]1

Participants

7

Reactant 6

HCID 311Citric AcidHCID 312ChlorideHCID 7503Benzyl ChlorideHCID 1189392-Bromo-4-fluorobenzonitrileHCID 5462224MagnesiumHCID 178507042HCID 178507042, compound

Product 1

HCID 205595051-(2-Bromo-4-fluorophenyl)-2-phenylethanone

Sources & evidence

ORD record
ord-b9accc49f44b427080c1319b506bb3d1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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