Hydrochloric Acid → 5-{4-[6-(4-Benzoylaminophenoxy)-1-methyl-1H-benzimidazole-2-ylmethoxy]benzyl}thiazolidine-2,4-dione

HRID 1555152Notes

Reaction equation

HRID 1555152 reaction equation
[C:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)(=[O:15])[Cl:16].[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:53][N:54]([CH3:55])[CH:56]=[O:57].[ClH:17].[ClH:18].[NH2:19][c:20]1[cH:21][cH:22][c:23]([O:24][c:25]2[cH:26][cH:27][c:28]3[c:29]([n:30]([CH3:49])[c:31]([CH2:33][O:34][c:35]4[cH:36][cH:37][c:38]([CH2:39][CH:40]5[C:41](=[O:46])[NH:42][C:43](=[O:45])[S:44]5)[cH:47][cH:48]4)[n:32]3)[cH:50]2)[cH:51][cH:52]1>>[C:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)(=[O:15])[NH:19][c:20]1[cH:21][cH:22][c:23]([O:24][c:25]2[cH:26][cH:27][c:28]3[c:29]([n:30]([CH3:49])[c:31]([CH2:33][O:34][c:35]4[cH:36][cH:37][c:38]([CH2:39][CH:40]5[C:41](=[O:46])[NH:42][C:43](=[O:45])[S:44]5)[cH:47][cH:48]4)[n:32]3)[cH:50]2)[cH:51][cH:52]1

Participants

6

Reactant 5

HCID 313Hydrochloric Acid2×HCID 6228DimethylformamideHCID 7412Benzoyl chlorideHCID 8471TriethylamineHCID 865877695-[[4-[[6-(4-Aminophenoxy)-1-methylbenzimidazol-2-yl]methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

Product 1

HCID 185375725-{4-[6-(4-Benzoylaminophenoxy)-1-methyl-1H-benzimidazole-2-ylmethoxy]benzyl}thiazolidine-2,4-dione

Sources & evidence

ORD record
ord-326eacad65be412898c3848c2782e2f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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