Chloride → 4-[4-({6-[5-(Methylsulfonyl)indolin-1-yl]pyrimidin-4-yl}oxy)piperidin-1-yl]-4-oxobutan-2-ol
Reaction equation
[CH3:18][O:19][c:20]1[n:21][c:22]([N+:23]2([CH3:24])[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2)[n:30][c:31]([O:32][CH3:33])[n:34]1.[CH3:1][CH:2]([OH:3])[CH2:4][C:5]([OH:6])=[O:7].[CH3:36][S:37](=[O:38])(=[O:39])[c:40]1[cH:41][c:42]2[c:46]([cH:47][cH:48]1)[N:45]([c:49]1[n:50][cH:51][n:52][c:53]([O:55][CH:56]3[CH2:57][CH2:58][NH:59][CH2:60][CH2:61]3)[cH:54]1)[CH2:44][CH2:43]2.[CH3:63][CH2:64][OH:65].[CH:8]([N:9]([CH:10]([CH3:11])[CH3:12])[CH2:13][CH3:14])([CH3:15])[CH3:16].[Cl-:17].[ClH:35].[OH2:62]>>[CH3:1][CH:2]([OH:3])[CH2:4][C:5](=[O:7])[N:59]1[CH2:58][CH2:57][CH:56]([O:55][c:53]2[n:52][cH:51][n:50][c:49]([N:45]3[CH2:44][CH2:43][c:42]4[cH:41][c:40]([S:37]([CH3:36])(=[O:38])=[O:39])[cH:48][cH:47][c:46]43)[cH:54]2)[CH2:61][CH2:60]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-3d0ff1be767d4e0b93fcc3da1184c52d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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