Hydrochloric Acid → 4'-({4-[4-hydroxy-4-(tetrahydro-2H-pyran-4-yl)cyclohexyl]-5-oxo-7-propyl-4,5-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-6-yl}methyl)biphenyl-2-carbonitrile
Reaction equation
[Br:9][CH2:10][CH2:11][Br:12].[Cl:2][CH:3]1[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1.[ClH:48].[Mg:1].[O:13]=[c:14]1[n:15]([CH:41]2[CH2:42][CH2:43][C:44](=[O:47])[CH2:45][CH2:46]2)[c:16]2[n:17]([c:18]([CH2:35][CH2:36][CH3:37])[c:19]1[CH2:20][c:21]1[cH:22][cH:23][c:24](-[c:27]3[c:28]([C:33]#[N:34])[cH:29][cH:30][cH:31][cH:32]3)[cH:25][cH:26]1)[n:38][cH:39][n:40]2.[O:49]1[CH2:50][CH2:51][CH2:52][CH2:53]1>>[CH:3]1([C:44]2([OH:47])[CH2:43][CH2:42][CH:41]([n:15]3[c:14](=[O:13])[c:19]([CH2:20][c:21]4[cH:22][cH:23][c:24](-[c:27]5[c:28]([C:33]#[N:34])[cH:29][cH:30][cH:31][cH:32]5)[cH:25][cH:26]4)[c:18]([CH2:35][CH2:36][CH3:37])[n:17]4[c:16]3[n:40][cH:39][n:38]4)[CH2:46][CH2:45]2)[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e6fea1c88a3741eeab2c422a265a5aa3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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