Hydrochloric Acid → Methyl-[1-(4-trifluoromethyl-phenyl)-piperidin-4-ylmethyl]-amine
Reaction equation
[Al+3:27].[C:1]([O:2][C:6](=[O:3])[NH:7][CH2:8][CH:9]1[CH2:10][CH2:11][N:12]([c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[CH2:13][CH2:14]1)([CH3:4])([CH3:5])[CH3:25].[ClH:32].[H-:26].[H-:29].[H-:30].[H-:31].[Li+:28].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[CH3:6][NH:7][CH2:8][CH:9]1[CH2:10][CH2:11][N:12]([c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[CH2:13][CH2:14]1Participants
7
Sources & evidence
- ORD record
- ord-18f515f628e644089aab3821bcea999b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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