Chloride → 1-(5-bromopyridin-2-yl)-5-[4-(cyclopropylsulfonyl)phenyl]-6-(tetrahydro-2H-pyran-4-yl)hexane-1,4-dione
Reaction equation
[Br:25][c:26]1[cH:27][cH:28][c:29]([CH:32]=[O:33])[n:30][cH:31]1.[CH2:45]([n+:46]1[c:47]([CH3:48])[c:49]([CH2:50][CH2:51][OH:52])[s:53][cH:54]1)[c:55]1[cH:56][cH:57][cH:58][cH:59][cH:60]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:41][CH2:42][OH:43].[CH3:61][CH2:62][O:63][C:64](=[O:65])[CH3:66].[CH:1]1([S:4](=[O:5])(=[O:6])[c:7]2[cH:8][cH:9][c:10]([CH:13]([C:14]([CH:15]=[CH2:16])=[O:17])[CH2:18][CH:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[cH:11][cH:12]2)[CH2:2][CH2:3]1.[Cl-:44]>>[CH:1]1([S:4](=[O:5])(=[O:6])[c:7]2[cH:8][cH:9][c:10]([CH:13]([C:14]([CH2:15][CH2:16][C:32]([c:29]3[cH:28][cH:27][c:26]([Br:25])[cH:31][n:30]3)=[O:33])=[O:17])[CH2:18][CH:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[cH:11][cH:12]2)[CH2:2][CH2:3]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-ede0cac39e424eb0af259907b2452e08
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…