Bromide ion → 2,3-Dihydro-1-benzofuran-6-carboxylic acid

HRID 1558914Notes

Reaction equation

HRID 1558914 reaction equation
[Br-:30].[Br-:31].[C:14]=[O:15].[CH3:16][O:17][C:18](=[O:19])[c:20]1[cH:21][c:22]2[c:23]([cH:27][cH:28]1)[CH2:24][CH2:25][O:26]2.[CH3:1][CH2:2][CH2:3][CH2:4][N:5]([CH2:6][CH2:7][CH2:8][CH3:9])[CH2:10][CH2:11][CH2:12][CH3:13].[ClH:29].[Na+:72].[OH-:71].[Pd+2:70].[c:32]1([P:33]([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[cH:46][cH:47][cH:48][cH:49][cH:50]1.[c:51]1([P:52]([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[cH:65][cH:66][cH:67][cH:68][cH:69]1>>[O:17]=[C:18]([OH:19])[c:20]1[cH:21][c:22]2[c:23]([cH:27][cH:28]1)[CH2:24][CH2:25][O:26]2

Participants

10

Reactant 9

HCID 259Bromide ion2×HCID 313Hydrochloric AcidHCID 712FormaldehydeHCID 923Sodium ionHCID 961HydroxideHCID 7622TributylamineHCID 11776Triphenylphosphine2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 59942373Methyl 2,3-dihydro-1-benzofuran-6-carboxylate

Product 1

HCID 184145742,3-Dihydro-1-benzofuran-6-carboxylic acid

Sources & evidence

ORD record
ord-4bc8241db2884b63a5956e5a715a0790
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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