Dimethylformamide → 1-[3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-ol
Reaction equation
[CH:22]([N:23]([CH2:24][CH3:25])[CH:26]([CH3:27])[CH3:28])([CH3:29])[CH3:30].[Cl:8][c:9]1[cH:10][cH:11][c:12]2[n:13]([n:14]1)[c:15]([C:18]([F:19])([F:20])[F:21])[n:16][n:17]2.[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[OH:1][CH:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([c:9]2[cH:10][cH:11][c:12]3[n:13]([n:14]2)[c:15]([C:18]([F:19])([F:20])[F:21])[n:16][n:17]3)[CH2:6][CH2:7]1Participants
5
Sources & evidence
- ORD record
- ord-ce749b8402244351be3a5f28ea375080
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…