Dimethylformamide → 3-[4-[2-(1-Azabicyclo[2.2.2]octan-3-yl)ethenyl]phenyl]-5-methyl-1,2,4-oxadiazole

HRID 1561978Notes

Reaction equation

HRID 1561978 reaction equation
[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[CH:14](=[CH2:15])[CH:16]1[CH2:17][N:18]2[CH2:19][CH2:20][CH:21]1[CH2:22][CH2:23]2.[Cu:36][I:37].[I:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][o:10][c:11]([CH3:13])[n:12]2)[cH:6][cH:7]1>>[c:2]1([CH:15]=[CH:14][CH:16]2[CH2:17][N:18]3[CH2:19][CH2:20][CH:21]2[CH2:22][CH2:23]3)[cH:3][cH:4][c:5](-[c:8]2[n:9][o:10][c:11]([CH3:13])[n:12]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 53147561-Azabicyclo[2.2.2]octane, 3-ethenyl-HCID 19703103HCID 19703103, compound

Product 1

HCID 676340713-[4-[2-(1-Azabicyclo[2.2.2]octan-3-yl)ethenyl]phenyl]-5-methyl-1,2,4-oxadiazole

Sources & evidence

ORD record
ord-8684df04a64649da9f79e9bc1f361896
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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