Hydroxide → N-(4-chloro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrazine-2-carboxamide
Reaction equation
[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11])[nH:12][cH:13][c:14]2[NH2:15].[Cl:34][CH2:35][Cl:36].[Li+:33].[OH-:32].[OH2:37].[n:16]1[c:17]([C:22](=[O:23])[OH:24])[cH:18][n:19][cH:20][cH:21]1>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11])[nH:12][cH:13][c:14]2[NH:15][C:22]([c:17]1[n:16][cH:21][cH:20][n:19][cH:18]1)=[O:23]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-f15d566ff54e43bc92564af40da6dbc8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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