Hydrochloric Acid → 3-[2-(4-{5-[1,1,1,3,3,3-Hexafluoro-2-(4-methoxybenzyloxy)propan-2-yl]-4-propylpyridin-2-yl}piperazin-1-yl)ethyl]-5-[4-(1-methylethoxy)phenyl]-5-methylimidazolidine-2,4-dione
Reaction equation
[CH3:38][C:39]1([c:46]2[cH:47][cH:48][c:49]([O:52][CH:53]([CH3:54])[CH3:55])[cH:50][cH:51]2)[C:40](=[O:45])[NH:41][C:42](=[O:44])[NH:43]1.[CH3:88][N:89]([CH3:90])[CH:91]=[O:92].[ClH:87].[F:1][C:2]([C:3]([C:4]([F:5])([F:6])[F:7])([O:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([O:16][CH3:17])[cH:14][cH:15]1)[c:18]1[c:19]([CH2:33][CH2:34][CH3:35])[cH:20][c:21]([N:24]2[CH2:25][CH2:26][N:27]([CH2:30][CH2:31][OH:32])[CH2:28][CH2:29]2)[n:22][cH:23]1)([F:36])[F:37].[O:75]=[C:76]([O:77][CH2:78][CH3:79])[N:80]=[N:81][C:82]([O:83][CH2:84][CH3:85])=[O:86].[OH2:93].[c:56]1([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[cH:70][cH:71][cH:72][cH:73][cH:74]1>>[F:1][C:2]([C:3]([C:4]([F:5])([F:6])[F:7])([O:8][CH2:9][c:10]1[cH:11][cH:12][c:13]([O:16][CH3:17])[cH:14][cH:15]1)[c:18]1[c:19]([CH2:33][CH2:34][CH3:35])[cH:20][c:21]([N:24]2[CH2:25][CH2:26][N:27]([CH2:30][CH2:31][N:41]3[C:40](=[O:45])[C:39]([CH3:38])([c:46]4[cH:47][cH:48][c:49]([O:52][CH:53]([CH3:54])[CH3:55])[cH:50][cH:51]4)[NH:43][C:42]3=[O:44])[CH2:28][CH2:29]2)[n:22][cH:23]1)([F:36])[F:37]Participants
8
Reactant 7
HCID 313Hydrochloric Acid
HCID 962Water
HCID 6228Dimethylformamide
HCID 11776Triphenylphosphine
HCID 220568ethyl N-ethoxycarbonyliminocarbamate
HCID 30521535-methyl-5-[4-(propan-2-yloxy)phenyl]imidazolidine-2,4-dione
HCID 866471802-(4-{5-[1,1,1,3,3,3-Hexafluoro-2-(4-methoxybenzyloxy)propan-2-yl]-4-propylpyridin-2-yl}piperazin-1-yl)ethanolProduct 1
Sources & evidence
- ORD record
- ord-6b9859ba526b4980856bb1e15e46ed76
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…