Water → 3-(1-cyano-1-methylethyl)-N-{4-methyl-3-[(2-{[(4-methylpiperazin-1-yl)acetyl]amino}[1,3]thiazolo[5,4-d]pyrimidin-5-yl)amino]phenyl}benzamide
Reaction equation
[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[CH3:44][N:45]1[CH2:46][CH2:47][NH:48][CH2:49][CH2:50]1.[Cl:1][CH2:2][C:3](=[O:4])[NH:5][c:6]1[s:7][c:8]2[n:9][c:10]([NH:15][c:16]3[cH:17][c:18]([NH:23][C:24]([c:25]4[cH:26][c:27]([C:31]([CH3:32])([CH3:33])[C:34]#[N:35])[cH:28][cH:29][cH:30]4)=[O:36])[cH:19][cH:20][c:21]3[CH3:22])[n:11][cH:12][c:13]2[n:14]1.[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1.[OH2:51]>>[CH2:2]([C:3](=[O:4])[NH:5][c:6]1[s:7][c:8]2[n:9][c:10]([NH:15][c:16]3[cH:17][c:18]([NH:23][C:24]([c:25]4[cH:26][c:27]([C:31]([CH3:32])([CH3:33])[C:34]#[N:35])[cH:28][cH:29][cH:30]4)=[O:36])[cH:19][cH:20][c:21]3[CH3:22])[n:11][cH:12][c:13]2[n:14]1)[N:48]1[CH2:47][CH2:46][N:45]([CH3:44])[CH2:50][CH2:49]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ea46f13f38b84e0e85dff8cc239af01c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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