Sodium ion → Ethyl 6-[6-(ethylcarbamoylamino)-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]-3-pyridinyl]-1-[1-(2-morpholin-4-ylethyl)piperidin-3-yl]-4-oxo-1,8-naphthyridine-3-carboxylate
Reaction equation
[C:69]([O:70][BH-:71]([O:72][C:73](=[O:74])[CH3:75])[O:76][C:77](=[O:78])[CH3:79])(=[O:80])[CH3:81].[CH2:1]([CH3:2])[NH:3][C:4]([NH:5][c:6]1[cH:7][c:8](-[c:34]2[s:35][cH:36][c:37]([C:39]([F:40])([F:41])[F:42])[n:38]2)[c:9](-[c:12]2[cH:13][c:14]3[c:15](=[O:33])[c:16]([C:28](=[O:29])[O:30][CH2:31][CH3:32])[cH:17][n:18]([CH:22]4[CH2:23][NH:24][CH2:25][CH2:26][CH2:27]4)[c:19]3[n:20][cH:21]2)[cH:10][n:11]1)=[O:43].[CH2:83]1[O:84][CH2:85][CH2:86][CH2:87]1.[CH:60]([N:61]([CH2:62][CH3:63])[CH:64]([CH3:65])[CH3:66])([CH3:67])[CH3:68].[F:44][C:45]([F:46])([F:47])[C:48]([OH:49])=[O:50].[Na+:82].[O:51]1[CH2:52][CH2:53][N:54]([CH2:57][CH:58]=[O:59])[CH2:55][CH2:56]1>>[CH2:1]([CH3:2])[NH:3][C:4]([NH:5][c:6]1[cH:7][c:8](-[c:34]2[s:35][cH:36][c:37]([C:39]([F:40])([F:41])[F:42])[n:38]2)[c:9](-[c:12]2[cH:13][c:14]3[c:15](=[O:33])[c:16]([C:28](=[O:29])[O:30][CH2:31][CH3:32])[cH:17][n:18]([CH:22]4[CH2:23][N:24]([CH2:58][CH2:57][N:54]5[CH2:53][CH2:52][O:51][CH2:56][CH2:55]5)[CH2:25][CH2:26][CH2:27]4)[c:19]3[n:20][cH:21]2)[cH:10][n:11]1)=[O:43]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-58c00ec6d06b41db9754bf15fb76e736
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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