1,2-Dichloroethane → N-[(3-Chloro-pyrazin-2-yl)-(4-phenoxy-phenyl)-methyl]-formamide

HRID 1568410Notes

Reaction equation

HRID 1568410 reaction equation
[CH2:1]([Cl:2])[CH2:3][Cl:4].[CH3:46][CH2:47][O:48][C:49]([CH3:50])=[O:51].[CH:37]([N:38]([CH2:39][CH3:40])[CH:41]([CH3:42])[CH3:43])([CH3:44])[CH3:45].[CH:58]([OH:59])=[O:60].[Cl:15][c:16]1[c:17]([CH:22]([c:23]2[cH:24][cH:25][c:26]([O:29][c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:27][cH:28]2)[NH2:36])[n:18][cH:19][cH:20][n:21]1.[Cl:52][CH2:53][Cl:54].[Cl:55][CH2:56][Cl:57].[OH:5][n:6]1[c:7]2[c:8]([cH:9][cH:10][cH:11][cH:12]2)[n:13][n:14]1>>[Cl:15][c:16]1[c:17]([CH:22]([c:23]2[cH:24][cH:25][c:26]([O:29][c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:27][cH:28]2)[NH:36][CH:47]=[O:48])[n:18][cH:19][cH:20][n:21]1

Participants

8

Reactant 7

HCID 111,2-DichloroethaneHCID 284Formic AcidHCID 6344Dichloromethane2×HCID 8857Ethyl AcetateHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 59341168HCID 59341168, compound

Product 1

HCID 86636036N-[(3-Chloro-pyrazin-2-yl)-(4-phenoxy-phenyl)-methyl]-formamide

Sources & evidence

ORD record
ord-a51ec23dd8da4e94b37b6075961bd616
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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