Ammonium → 4-(1H-Pyrazol-4-yl)-7-(2-(trimethylsilyl)ethoxy)methyl-7 H-pyrrolo(2,3-d)-pyrimidine

HRID 1568731Notes

Reaction equation

HRID 1568731 reaction equation
[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:32][C:33]#[N:34].[CH3:35][C:36]([CH3:37])([O-:38])[CH3:39].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[CH:1]1([CH:2]([CH2:3][C:4]#[N:5])[n:10]2[n:11][cH:12][c:13](-[c:15]3[c:16]4[c:17]([n:18][cH:19][n:20]3)[n:21]([CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:29])([CH3:30])[CH3:31])[cH:22][cH:23]4)[cH:14]2)[CH2:6][CH2:7][CH2:8][CH2:9]1.[Cl-:52].[K+:40].[NH4+:53]>>[nH:10]1[n:11][cH:12][c:13](-[c:15]2[c:16]3[c:17]([n:18][cH:19][n:20]2)[n:21]([CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:29])([CH3:30])[CH3:31])[cH:22][cH:23]3)[cH:14]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 813Potassium CationHCID 6342AcetonitrileHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 45749132-Methylpropan-2-olateHCID 574775973 Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2.3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile

Product 1

HCID 426313464-(1H-Pyrazol-4-yl)-7-(2-(trimethylsilyl)ethoxy)methyl-7 H-pyrrolo(2,3-d)-pyrimidine

Sources & evidence

ORD record
ord-9d2dadc7cf6248c3b38e9d34bfe191b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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