Acetate → 1-Furan-2-ylmethyl-6-methoxy-4-phenyl-phthalazine

HRID 1569278Notes

Reaction equation

HRID 1569278 reaction equation
[C:57]([O-:58])(=[O:59])[CH3:60].[C:62]([O-:63])(=[O:64])[CH3:65].[CH2:1]1[O:2][CH2:3][CH2:4][CH2:5]1.[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[Cl:13][c:14]1[n:15][n:16][c:17]([CH2:26][c:27]2[o:28][cH:29][cH:30][cH:31]2)[c:18]2[cH:19][cH:20][c:21]([O:24][CH3:25])[cH:22][c:23]12.[Pd+2:61].[c:32]1([P:33]([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[cH:46][cH:47][cH:48][cH:49][cH:50]1.[c:6]1([Li:12])[cH:7][cH:8][cH:9][cH:10][cH:11]1>>[c:6]1(-[c:14]2[n:15][n:16][c:17]([CH2:26][c:27]3[o:28][cH:29][cH:30][cH:31]3)[c:18]3[cH:19][cH:20][c:21]([O:24][CH3:25])[cH:22][c:23]23)[cH:7][cH:8][cH:9][cH:10][cH:11]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 11776TriphenylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 121090664-Chloro-1-furan-2-ylmethyl-6-methoxy-phthalazineHCID 178506676HCID 178506676, compound

Product 1

HCID 121090671-Furan-2-ylmethyl-6-methoxy-4-phenyl-phthalazine

Sources & evidence

ORD record
ord-0197cc2dd4ef48d78e7d10d429d402d9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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