Tetrahydrofuran → 4-(3-Fluoropyrazin-2-YL)tetrahydro-2H-pyran-4-OL
Reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH3:6][C:7]1([CH3:8])[CH2:9][CH2:10][CH2:11][C:12]([CH3:13])([CH3:14])[NH:15]1.[F:16][c:17]1[n:18][cH:19][cH:20][n:21][cH:22]1.[O:23]1[CH2:24][CH2:25][C:26](=[O:29])[CH2:27][CH2:28]1>>[F:16][c:17]1[n:18][cH:19][cH:20][n:21][c:22]1[C:26]1([OH:29])[CH2:25][CH2:24][O:23][CH2:28][CH2:27]1Participants
6
Sources & evidence
- ORD record
- ord-998169c41dd942318f873edba45a7f12
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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