Propargyl alcohol → HCID 6482389, compound

HRID 1571482Notes

Reaction equation

HRID 1571482 reaction equation
[CH2:24]([C:25]#[CH:26])[OH:27].[CH2:28]([NH:29][CH2:30][CH3:31])[CH3:32].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[c:11](=[O:21])[c:12]3[c:13]([n:14]([CH3:16])[cH:15]2)[s:17][c:18]([I:20])[cH:19]3)[cH:22][cH:23]1.[Cu:33]([I:34])[I:35].[Pd:36]([Cl:37])[Cl:38].[c:39]1([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[cH:53][cH:54][cH:55][cH:56][cH:57]1.[c:58]1([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[cH:72][cH:73][cH:74][cH:75][cH:76]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[c:11](=[O:21])[c:12]3[c:13]([n:14]([CH3:16])[cH:15]2)[s:17][c:18]([C:26]#[C:25][CH2:24][OH:27])[cH:19]3)[cH:22][cH:23]1

Participants

7

Reactant 6

HCID 7859Propargyl alcoholHCID 8021DiethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 83717Copper iodideHCID 10095695HCID 10095695, compound

Product 1

HCID 6482389HCID 6482389, compound

Sources & evidence

ORD record
ord-14c626aa8be24b999da1046ccc9dab1b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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