Acetate → 3-(Quinolin-3-yl)acrylic Acid Methyl Ester

HRID 1571883Notes

Reaction equation

HRID 1571883 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[cH:11]1.[C:12]([CH:13]=[CH2:14])(=[O:15])[O:16][CH3:17].[CH3:40][CH2:41][N:42]([CH2:43][CH3:44])[CH2:45][CH3:46].[CH:47]([Cl:48])([Cl:49])[Cl:50].[O-:52][C:53]([CH3:54])=[O:55].[O-:56][C:57]([CH3:58])=[O:59].[Pd+2:51].[c:18]1([CH3:19])[cH:20][cH:21][cH:22][cH:23][c:24]1[P:25]([c:26]1[cH:27][cH:28][cH:29][cH:30][c:31]1[CH3:32])[c:33]1[cH:34][cH:35][cH:36][cH:37][c:38]1[CH3:39]>>[c:2]1([CH:14]=[CH:13][C:12](=[O:15])[O:16][CH3:17])[cH:3][n:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[cH:11]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 6212ChloroformHCID 7294Methyl AcrylateHCID 8471TriethylamineHCID 214133-BromoquinolineHCID 80271Tri-o-tolylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 6027563-(Quinolin-3-yl)acrylic Acid Methyl Ester

Sources & evidence

ORD record
ord-960efac690a74a8eb187a3265d17e584
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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