Trifluoroacetic acid → [2-(2,3-Dihydro-1H-isoindol-4-yloxy)-ethyl]-dimethyl-amine

HRID 1572139Notes

Reaction equation

HRID 1572139 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([O:21][CH3:22])[cH:23][cH:24][c:25]1[CH2:26][N:6]1[CH2:7][c:8]2[cH:9][cH:10][cH:11][c:12]([O:15][CH2:16][CH2:17][N:18]([CH3:19])[CH3:20])[c:13]2[CH2:14]1.[CH3:34][O:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1.[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[OH:27][C:28]([C:29]([F:30])([F:31])[F:32])=[O:33]>>[NH:6]1[CH2:7][c:8]2[cH:9][cH:10][cH:11][c:12]([O:15][CH2:16][CH2:17][N:18]([CH3:19])[CH3:20])[c:13]2[CH2:14]1

Participants

5

Reactant 4

HCID 6422Trifluoroacetic acidHCID 7519AnisoleHCID 8857Ethyl AcetateHCID 592631072-(2,4-Dimethoxy-benzyl)-4-(2-dimethylamino-ethoxy)-2,3-dihydro-1H-isoindole

Product 1

HCID 46915187[2-(2,3-Dihydro-1H-isoindol-4-yloxy)-ethyl]-dimethyl-amine

Sources & evidence

ORD record
ord-6ccefc012d2d4ab2b42b3807d97726fa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…