Hydrochloric Acid → 8-(2,4-dimethoxybenzyl)-4-(4-(1-(2-(pyrrolidin-1-yl)ethyl)-4-(trifluoromethyl)-1H-imidazol-2-yl)piperidin-1-yl)-5-(trifluoromethyl)-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one
Reaction equation
[CH3:53][N:54]1[CH2:55][CH2:56][CH2:57][C:58]1=[O:59].[CH:60]([N:61]([CH:62]([CH3:63])[CH3:64])[CH2:65][CH3:66])([CH3:67])[CH3:68].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[N:8]([CH2:17][c:18]1[c:19]([O:26][CH3:27])[cH:20][c:21]([O:24][CH3:25])[cH:22][cH:23]1)[C:9](=[O:16])[CH2:10][CH:11]2[C:12]([F:13])([F:14])[F:15].[ClH:28].[ClH:29].[ClH:30].[N:31]1([CH2:36][CH2:37][n:38]2[c:39]([CH:47]3[CH2:48][CH2:49][NH:50][CH2:51][CH2:52]3)[n:40][c:41]([C:43]([F:44])([F:45])[F:46])[cH:42]2)[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH2:69]>>[c:2]1([N:50]2[CH2:49][CH2:48][CH:47]([c:39]3[n:38]([CH2:37][CH2:36][N:31]4[CH2:32][CH2:33][CH2:34][CH2:35]4)[cH:42][c:41]([C:43]([F:44])([F:45])[F:46])[n:40]3)[CH2:52][CH2:51]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[N:8]([CH2:17][c:18]1[c:19]([O:26][CH3:27])[cH:20][c:21]([O:24][CH3:25])[cH:22][cH:23]1)[C:9](=[O:16])[CH2:10][CH:11]2[C:12]([F:13])([F:14])[F:15]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-241a885fff844a5f8370fca26ca02014
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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