Chloride → 3-(1-Carboxycyclopentyl)-2-methylenepropanoic acid t-butyl ester

HRID 1572439Notes

Reaction equation

HRID 1572439 reaction equation
[Br:9][CH2:10][C:11]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[CH2:19].[CH:1]1([C:6](=[O:7])[OH:8])[CH2:2][CH2:3][CH2:4][CH2:5]1.[Cl-:25].[Cl-:27].[O:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1.[Zn+2:26]>>[C:1]1([C:6](=[O:7])[OH:8])([CH2:19][C:11](=[CH2:10])[C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

6

Reactant 5

HCID 312Chloride2×HCID 8028TetrahydrofuranHCID 18840Cyclopentanecarboxylic acidHCID 32051Zinc(2+)HCID 10955115Tert-butyl 2-(bromomethyl)prop-2-enoate

Product 1

HCID 540038933-(1-Carboxycyclopentyl)-2-methylenepropanoic acid t-butyl ester

Sources & evidence

ORD record
ord-0f077a2dc6104379b9f66569c1763b18
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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