Tetrahydrofuran → 2-(3,4-Dichlorophenyl)-3-[2-oxo-2-(1-piperidinyl)ethyl]-3H-imidazo[4,5-b]pyridine
Reaction equation
[C:22]([n:23]1[cH:24][cH:25][n:26][cH:27]1)([n:28]1[cH:29][cH:30][n:31][cH:32]1)=[O:33].[CH2:34]1[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]1.[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]3[c:12]([n:13][cH:14][cH:15][cH:16]3)[n:17]2[CH2:18][C:19](=[O:20])[OH:21])[cH:5][cH:6][c:7]1[Cl:8].[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]3[c:12]([n:13][cH:14][cH:15][cH:16]3)[n:17]2[CH2:18][C:19](=[O:20])[N:37]2[CH2:36][CH2:35][CH2:34][CH2:39][CH2:38]2)[cH:5][cH:6][c:7]1[Cl:8]Participants
5
Sources & evidence
- ORD record
- ord-3b8b611766aa4144868ab3527bc4b2c5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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