Pyridine → HCID 12398505, compound

HRID 1576924Notes

Reaction equation

HRID 1576924 reaction equation
Cl[C:2]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)=[O:3].[CH3:18][CH:19]([OH:21])[CH3:20].N1C=CC=CC=1.C1(C)C(C)=CC=CC=1>O>[CH:19]([O:21][C:2]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)=[O:3])([CH3:20])[CH3:18]

Participants

6

Reactant 4

HCID 1049PyridineHCID 3776IsopropanolHCID 7237O-XyleneHCID 37664104-Benzyloxybenzoylchloride

Product 1

HCID 12398505HCID 12398505, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 4-chlorocarbonylphenoxy phenyl methane (12.3g.; 0.05 mole), propan-2-ol (3.6g.; 0.6 mole), pyridine (5g) and xylene (50ml) were boiled under reflux for 18hr. The cooled mixture was poured into water and extracted with dichloromethane. The organic extract was washed well with water and dried (anhyd. MgSO4), filtration and evaporation yielded 4-isopropoxycarbonylphenoxy phenyl methane, m.p. 62°-3°C.

Workup

  1. temperatureunder reflux for 18hr
  2. extractionextracted with dichloromethane
  3. extractionThe organic extract
  4. washwas washed well with water
  5. customdried
  6. filtration(anhyd. MgSO4), filtration and evaporation

Sources & evidence

ORD record
ord-fdb3f11995c74d6388043edfd4481038
Source dataset
uspto-grants-1976_09
Patent number
US03983164

Reaction notes

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