反应详情

A mixture of 19.9 g of phenothiazine, 14 g of 3-(imidazol-1-yl)-propionic acid, 20.6 g of dicyclohexylcarbodiimide, and 200 ml of ethyl acetate is stirred for 30 minutes at 0°, and then for 3 hours at 20°. It is worked up in the customary manner to give 10-[3-(imidazol-1-yl)-propionyl]-phenothiazine, melting point 150°-152°.

1. waitfor 3 hours at 20°