Hydrochloric Acid → HCID 22718382, compound

HRID 1582582Notes

Reaction equation

HRID 1582582 reaction equation
[C:1]1([S:7]([C:10]2[N:11]=[C:12]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[CH3:27])[O:13][C:14]=2[N:15]2[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:28]>O1CCCC1.CO>[ClH:28].[C:1]1([S:7]([C:10]2[N:11]=[C:12]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[CH3:27])[O:13][C:14]=2[N:15]2[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 10271308HCID 10271308, compound

Product 1

HCID 22718382HCID 22718382, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

1-(4-Phenylsulfonyl-2-o-tolyl-oxazol-5-yl)piperazine (0.2 g, 0.556 mmol) was dissolved in tetrahydrofuran (15 ml) and methanol (15 ml), mixed with methanolic hydrochloric acid (2 ml) at room temperature and subsequently stirred for 1 h. The precipitated crystals were filtered off with suction, washed with a small amount of tetrahydrofuran and dried in air.

Workup

  1. filtrationThe precipitated crystals were filtered off with suction
  2. washwashed with a small amount of tetrahydrofuran
  3. customdried in air

Sources & evidence

ORD record
ord-42c08016b9dd4071a99d9f3c08549d64
Source dataset
uspto-grants-2004_05
Patent number
US06737426B1

Reaction notes

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