Thymine → HCID 86759453, compound

HRID 1582933Notes

Reaction equation

HRID 1582933 reaction equation
[NH:1]1[CH:9]=[C:7]([CH3:8])[C:5](=[O:6])[NH:4][C:2]1=[O:3].[CH3:10][O:11][C:12](=[O:18])[CH2:13][S:14][CH2:15][CH2:16]Br.C(OC(C)C)(C)C>>[CH3:10][O:11][C:12](=[O:18])[CH2:13][S:14][CH2:15][CH2:16][N:1]1[CH:9]=[C:7]([CH3:8])[C:5](=[O:6])[NH:4][C:2]1=[O:3]

Participants

4

Reactant 3

HCID 1135ThymineHCID 7914Diisopropyl EtherHCID 20727892HCID 20727892, compound

Product 1

HCID 86759453HCID 86759453, compound

Procedure

(I-7, Compound of Formula I, Where R1 is [2-[5-methyl-2,4-1H,3H-pyrimidinedione-1-yl]ethyl]thio) p A] [[2-[5-Methyl-2,4-(1H,3H)-pyrimidinedione-1-yl]ethyl]thio]acetic acid methyl ester was synthesized from thymine and [[2-bromoethyl]thio]acetic acid methyl ester as described in example 6A. Mp: 75° C. (diisopropyl ether).

Sources & evidence

ORD record
ord-709c373bbca74cd093e1da56f1c50bea
Source dataset
uspto-grants-2004_05
Patent number
US06740642B2

Reaction notes

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