Hydrochloric Acid → HCID 20258953, compound

HRID 1583534Notes

Reaction equation

HRID 1583534 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8].[C:9]1(=O)[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1.[ClH:16]>C(O)C.C(O)(C)C.O=[Pt]=O>[ClH:16].[CH:9]1([NH:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[OH:8])[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

Participants

7

Reactant 3

HCID 313Hydrochloric AcidHCID 58012-AminophenolHCID 7967Cyclohexanone

Product 1

HCID 20258953HCID 20258953, compound

Reagents, catalysts & solvents 3

HCID 345198Adams' catalystCatalystHCID 702EthanolSolventHCID 3776IsopropanolSolvent

Procedure

A mixture of 10.9 g (0.1 mol) of 2-aminophenol and 10.4 g (0.1 mol) of cyclohexanone in 200 ml of ethanol is hydrogenated over 0.2 g of PtO2 under standard conditions, 0.1 mol of HCl in isopropanol is added to the reaction mixture, the catalyst is filtered off and the filtrate is evaporated in vacuo and the residue is precipitated with ether.

Workup

  1. additionis added to the reaction mixture
  2. filtrationthe catalyst is filtered off
  3. customthe filtrate is evaporated in vacuo
  4. customthe residue is precipitated with ether

Sources & evidence

ORD record
ord-58822e9c001f4e41bcb5a916632fdeb1
Source dataset
uspto-grants-1985_11
Patent number
US04552874

Reaction notes

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