Dimethylformamide → 2-(Methoxymethyl)-N-(5-methylpyridin-2-yl)-4-[4-(methylsulfonyl)-phenoxy]-1-benzofuran-6-carboxamide

HRID 158379Notes

Reaction equation

HRID 158379 reaction equation
[CH3:1][O:2][CH2:3][c:4]1[o:5][c:6]2[c:7]([cH:8]1)[c:9]([O:16][c:17]1[cH:18][cH:19][c:20]([S:23](=[O:24])(=[O:25])[CH3:26])[cH:21][cH:22]1)[cH:10][c:11]([C:13](=[O:14])[OH:15])[cH:12]2.[CH:51]([N:52]([CH2:53][CH3:54])[CH:55]([CH3:56])[CH3:57])([CH3:58])[CH3:59].[NH2:60][c:61]1[n:62][cH:63][c:64]([CH3:67])[cH:65][cH:66]1.[O:68]=[CH:69][N:70]([CH3:71])[CH3:72].[P-:27]([F:28])([F:29])([F:30])([F:31])([F:32])[F:33].[n:34]1([O:35][C:36]([N:37]([CH3:38])[CH3:39])=[N+:40]([CH3:41])[CH3:42])[c:43]2[n:44][cH:45][cH:46][cH:47][c:48]2[n:49][n:50]1>>[CH3:1][O:2][CH2:3][c:4]1[o:5][c:6]2[c:7]([cH:8]1)[c:9]([O:16][c:17]1[cH:18][cH:19][c:20]([S:23](=[O:24])(=[O:25])[CH3:26])[cH:21][cH:22]1)[cH:10][c:11]([C:13](=[O:14])[NH:60][c:61]1[n:62][cH:63][c:64]([CH3:67])[cH:65][cH:66]1)[cH:12]2

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 153482-Amino-5-methylpyridineHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 667559132-(Methoxymethyl)-4-(4-(methylsulfonyl)phenoxy)benzofuran-6-carboxylic acid

Product 1

HCID 667565212-(Methoxymethyl)-N-(5-methylpyridin-2-yl)-4-[4-(methylsulfonyl)-phenoxy]-1-benzofuran-6-carboxamide

Sources & evidence

ORD record
ord-0046d9f8dd694beabc8ab73ef644422e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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